Dysplasia epiphysealis hemimelica (Trevor’s disease): a rare case report with oral manifestations.

Dysplasia epiphysealis hemimelica, also known as Trevor’s disease, is an extremely rare skeletal developmental disorder of unknown etiology, characterized by an osteocartilaginous outgrowth of one or more epiphyses or of a tarsal bone during childhood. It is a rare skeletal hemimelica disorder characterized by asymmetric growth of cartilage in one or more epiphyses. Due to the unusual presentation and variability of the picture, there is no standardized treatment and outcome is very different. Also such an unusual, unique case with craniofacial manifestations has not been reported in the literature. We report a case of a 14-year-old male, who complained of irregularly placed teeth in upper and lower front teeth region. On general physical examination we noticed some skeletal abnormalities with the patient and hence we subjected him to radiographic investigations. The images were consistent with epiphyseal dysplasia hemimelica. The prognosis of DEH is variable and depends basically on its location and size. Carriers of this unusual dysplasia should be periodically monitored for the risk of recurrence.

The Effect of Sodium Hypochlorite Treatment On The Shear Bond Strength of An Acetone - Based Adhesive System to Dentin - An In Vitro Study.

Aim: The aim of the present study was to evaluate the effects of different concentrations of sodium hypochlorite applied for 30 seconds on acid etched dentin on the shear bond strengths of an acetone-based adhesive. Materials and Methods: 40 freshly extracted molars were used as specimens to evaluate shear bond strength of composite to sodium hypochlorite (NaOCl)-treated dentin using Prime and Bond NT dentin bonding agent after 10% NaOCl (Group I), 5% NaOCl (Group II), 2.5% NaOCl (Group III) and No NaOCl (Control) treatment. Shear bond strengths of all specimens were measured using an Intron Universal Testing Machine. Results: Group II demonstrated higher bond strengths than Groups I, III and IV. Groups I, III and IV did not show any statistically significant differences in their bond strengths. Group III demonstrated the least bond strength. Group I showed similar bond strength as that of Group IV. Conclusion: Highest shear bond strength values were demonstrated by Group II i.e. 5% sodium hypochlorite treatment group. This could be because of partial decollagenation and formation of an optimum hybrid layer.

Changing pattern of nasal carriage of staphylococcus aureus in undergraduate medical students.

Staphylococcus aureus is the most common pathogen in nosocomial infections (4-6,17,19). Nasal carriage of Staphylococcus aureus is now considered a well defined risk factor for subsequent infections in various groups of patients (5,8,12,19). Nasal carriage of the pathogen among hospital personnel is an important source of nosocomial infection (1.3.18). Very few dedicated studies have investigated the nasal carriage state among medical students (3,18,21). Incidence of Staphylococcus aureus in the nasal flora of medical students, with or without varying degrees of clinical exposures were determined in our study. Nasal cultures from these students demonstrated a significantly increasing rate of colonization of Staphylococcus aureus with increased clinical exposure and also a corresponding increase in Methicillin resistance.

The effect of ibuprofen on bleeding during periodontal surgery.

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used medications for both medical and dental ailments. These drugs have been shown to increase bleeding during surgeries, which may prompt practitioners to discontinue their use before surgical procedures. The aim of the present study is to assess the effect of a common NSAID, ibuprofen, on bleeding during periodontal surgery. MATERIALS AND METHODS: The study group consisted of 10 patients who were scheduled to undergo periodontal surgery of similar type, complexity, and duration. Each subject acted as control as well as case group. The case group consisted of 10 surgeries in which patients were administered ibuprofen prior to surgery, whereas ibuprofen was not administered in control group. Bleeding time was measured at first visit and prior to first and second surgeries. The volume of blood loss during each surgery was measured by subtracting the amount of water used for irrigation from the total volume of fluid collected in the portable aspirator at the end of the surgery. RESULTS: The result showed a statistically significant (P < 0.05) increase in intraoperative bleeding during periodontal surgery when ibuprofen was preadministered. In addition, there was statistically significant (P < 0.05) increase in bleeding time. CONCLUSION: Ibuprofen taken prior to periodontal surgery increases intraoperative bleeding and should be administered cautiously before periodontal surgeries.

A novel trigger for acute coronary syndromes: the effect of lunar cycles on the incidence and in-hospital prognosis of acute coronary syndromes--a 3-year retrospective study.

Circadian variations in the incidence of hypertension and coronary events are well known with early morning surges. Effect of lunar cycles on various medical illnesses like seizures and psychiatric disturbances are documented. However, the effect of lunar cycles on coronary events has been sparsely documented. The authors studied the incidence of acute coronary events and admission patterns in the departments of emergency medicine and cardiology. Inclusion criteria included unstable angina, non-ST elevation myocardial infarction (MI) and ST elevation MI. Exclusion criteria included chest pain syndromes which were subsequently deemed non-cardiac by invasive or non-invasive investigations. Data from 1999 to 2001 were analysed. Admissions on full moon days were compared with those on new moon days. There were 30 full moon days and 30 new moon days and 223 admissions on full moon days and 266 on new moon days. This difference was statistically significant [p = .005]. Sixty-seven per cent were males and the rest were females. Subgroup analysis of mortality, postinfarction angina, effect on diabetics and hypertensives were done which showed an increased trend in new moon days. It is concluded that there is increased incidence of acute coronary events associated with new moon days.